Short Description

NGS genetic DNA test detecets for variant and mutation detection in ABCB1 gene for Colchicine resistance

PreTest Information

Clinical History of Patient who is going for ABCB1 Gene Colchicine resistance NGS Genetic DNA Test A Genetic Counselling session to draw a pedigree chart of family members affected with Colchicine resistance

Detail Description

ABCBI Gene Colchicine Resistance NGS Genetic DNA Test Cost INR: 20000 - Symptoms and Diagnosis

ABCBI gene is a protein-coding gene that is responsible for encoding the P-glycoprotein, a transporter protein that pumps out toxins and drugs from cells. The ABCBI gene plays a crucial role in multidrug resistance in cancer cells. Colchicine resistance is a condition where a patient's body does not respond to colchicine treatment, which is commonly used for gout and other inflammatory conditions. The ABCBI gene is known to be associated with colchicine resistance.

The NGS Genetic DNA test is a comprehensive test that analyzes a patient's DNA to determine if they have a genetic predisposition to colchicine resistance. This test is highly accurate and can help doctors make informed decisions about treatment options. The cost of this test in India is around INR 20,000, which is a reasonable cost compared to other genetic tests available in the market.

Symptoms of Colchicine Resistance

Colchicine resistance can be difficult to diagnose because it shares many symptoms with other inflammatory conditions. The symptoms of colchicine resistance may include:

• Severe pain and swelling in the joints
• Redness and warmth in the affected area
• Fever and chills
• Difficulty moving the affected joint

If you experience any of these symptoms, it is important to see a doctor as soon as possible to determine the underlying cause of your symptoms.

Diagnosis of Colchicine Resistance

Diagnosing colchicine resistance can be challenging because it is a rare condition. Doctors will typically perform a physical exam and run blood tests to rule out other possible causes of your symptoms. If your doctor suspects that you may have colchicine resistance, they may recommend the NGS Genetic DNA test to confirm the diagnosis.

Conclusion

The ABCBI gene is an important gene that plays a crucial role in multidrug resistance in cancer cells. Colchicine resistance is a condition that can be caused by a mutation in the ABCBI gene. The NGS Genetic DNA test is a highly accurate test that can help doctors diagnose colchicine resistance and make informed decisions about treatment options. If you are experiencing symptoms of colchicine resistance, it is important to see a doctor as soon as possible to determine the underlying cause of your symptoms.

Testing for the ABCB1 gene, specifically for colchicine resistance, involves using next-generation sequencing (NGS) to analyze an individual's DNA for variations or mutations in the ABCB1 gene. Colchicine is a medication commonly used to treat gout and certain inflammatory conditions. Some individuals may have variations in the ABCB1 gene that affect the way their bodies respond to colchicine treatment.