Short Description

Women with Non-classical Congenital Hyperplasia (NC-CAH) due to 21-hydroxylase deficiency and women with Polycystic Ovarian Syndrome (PCOS) have similar clinical presentation, with hyperandrogenism, oligomenorrhea and polycystic ovaries. As line of treatment may differ in the two conditions, it is recommended to differentiate NC-CAH from PCOS. This test helps to distinguish NC-CAH from PCOS.

PreTest Information

Overnight fasting is mandatory. First basal sample will be taken between 8-10 am. For menstruating females, sample should be given in first 10 days of the menstrual cycle.

Detail Description

17-HYDROXYPROGESTERONE (17ƒ??OHP) STIMULATION BY ACTH Test: Cost, Symptoms, and Diagnosis

17-Hydroxyprogesterone (17ƒ??OHP) is a hormone produced by the adrenal gland and ovaries in females. It plays a vital role in the production of other hormones such as cortisol and testosterone. The 17ƒ??OHP stimulation test is a diagnostic test that measures the level of 17ƒ??OHP in the blood after the administration of adrenocorticotropic hormone (ACTH).

What is the 17ƒ??OHP stimulation test?

The 17ƒ??OHP stimulation test is a blood test that measures the level of 17ƒ??OHP in the blood before and after the administration of ACTH. ACTH is a hormone that stimulates the adrenal gland to produce cortisol and other hormones. The test is used to diagnose disorders of the adrenal gland, such as congenital adrenal hyperplasia (CAH), which is a genetic disorder that affects the production of cortisol and other hormones.

What are the symptoms of CAH?

The symptoms of CAH depend on the severity of the condition and the age of the individual. In infants, symptoms may include:

• Dehydration
• Vomiting
• Weight loss
• Failure to thrive

In older children and adults, symptoms may include:

• Early puberty
• Irregular periods
• Excessive hair growth
• Acne
• Infertility

How is the 17ƒ??OHP stimulation test performed?

The 17ƒ??OHP stimulation test is a simple blood test that can be performed at any laboratory. The test involves two blood draws, one before the administration of ACTH and one 60 minutes after the administration of ACTH. The cost of the test is INR 3042.

What do the test results mean?

The normal range for 17ƒ??OHP levels in the blood varies depending on the age and sex of the individual. In general, normal levels of 17ƒ??OHP are between 0.2 and 2.5 ng/mL. Elevated levels of 17ƒ??OHP after the administration of ACTH may indicate a disorder of the adrenal gland, such as CAH.

Conclusion

The 17ƒ??OHP stimulation test is a simple blood test that can help diagnose disorders of the adrenal gland, such as CAH. The test is performed by measuring the level of 17ƒ??OHP in the blood before and after the administration of ACTH. Elevated levels of 17ƒ??OHP after the administration of ACTH may indicate a disorder of the adrenal gland. The cost of the test is INR 3042.

If you are experiencing symptoms of CAH or suspect that you may have a disorder of the adrenal gland, it is important to speak with your healthcare provider. They can help determine if the 17ƒ??OHP stimulation test is right for you and provide guidance on next steps.

For more information on the 17ƒ??OHP stimulation test or other diagnostic tests, contact DNA Labs India.